Macrophage Infection by HIV:
Implications for Pathogenesis and Cure
October 13-14, 2021
The National Institute of Mental Health’s (NIMH) Division of AIDS Research and the Ragon Institute of MGH, MIT, and Harvard are conducting a virtual meeting, “Macrophage Infection by HIV: Implications for Pathogenesis and Cure,” from October 13-14, 2021. While CD4+ T cells are the main targets of HIV infection, macrophages also become infected and resist the cytopathic effects of infection, contributing to HIV reservoir persistence. Furthermore, they drive inflammation and can contribute to the development of co-morbidities, including HIV-associated CNS dysfunction.
This meeting will examine emerging data related to macrophage interactions with the immune system during HIV infection, macrophage reservoirs and approaches to their elimination, and the involvement of CNS myeloid reservoirs and associated co-morbidities. The meeting will also highlight recent work on macrophage inflammation in the context of SARS-CoV-2 infection and work from new NIMH-funded investigators. A panel will discuss research gaps and priorities related to human macrophage reservoirs and inflammation/co-morbidities, and treatment strategies for HIV remission and cure.
Meeting Organizing Committee
Jeymohan Joseph, Ph.D.
Chief, HIV Neuropathogenesis and Therapeutics Branch
National Institute of Mental Health
Janice Clements, Ph.D.
Professor, Molecular and Comparative Pathobiology
Johns Hopkins Medicine International
Mario Stevenson, Ph.D.
Professor and Chief, Division of Infectious Diseases
University of Miami Miller School of Medicine
Kiera Clayton, Ph.D.
Assistant Professor, Department of Pathology
University of Massachusetts Medical School